I treat 3,5-Dimethylphenylboronic acid, CAS 172975-69-8, as a specialized aryl boronic acid used mainly as a coupling partner in organic synthesis. Its principal value is the boronic acid group, which can participate in palladium-catalyzed Suzuki–Miyaura reactions with suitable aryl or heteroaryl halides to form biaryl structures. For purchasing, I recommend checking identity, molecular weight, assay, physical form, packaging, documentation, and supplier support before comparing price alone.
This guide is intended for pharmaceutical, agrochemical, specialty chemical, medicinal chemistry, and research procurement teams. I explain what the material is, where it is commonly used, which specifications matter, how to evaluate suppliers, and how to reduce avoidable sourcing risk. Because product specifications can vary by manufacturer and batch, buyers should confirm the current certificate of analysis and commercial terms directly with the supplier.
I have prepared this guide for buyers who need 3,5-Dimethylphenylboronic acid for laboratory development, route scouting, process research, custom synthesis, or recurring production supply. It is also useful for procurement teams comparing several organic boronic acid suppliers. The guide is not a substitute for a project-specific stability assessment, process safety review, or regulatory evaluation.
Buyers usually need more than a chemical name and CAS number. They may also need a defined assay range, impurity profile, analytical data, suitable packaging, export documentation, and a realistic delivery schedule. A supplier that can answer these questions clearly is generally easier to qualify than one that only provides a basic product listing.
3,5-Dimethylphenylboronic acid is an aromatic boronic acid containing a phenyl ring substituted with methyl groups at the 3 and 5 positions and a boronic acid functional group. Its commonly listed molecular formula is C8H11BO2, and its calculated molecular weight is approximately 149.98 g/mol. The CAS number supplied for this material is 172975-69-8.
The boronic acid group is the chemically active feature used in many cross-coupling strategies. The two methyl substituents can influence steric and electronic properties in a target molecule, which may make this building block useful when a specific substitution pattern is required. Actual reaction performance depends on the coupling partner, catalyst system, base, solvent, temperature, water content, and work-up conditions.
In a typical Suzuki–Miyaura coupling, the boronic acid reacts with an aryl, heteroaryl, or vinyl halide under an appropriate catalytic system. The reaction forms a new carbon–carbon bond while the boronic acid portion is removed during the process. I recommend treating this description as a general synthetic role rather than a guarantee of performance in every reaction system.
Research chemists may use 3,5-Dimethylphenylboronic acid to introduce a substituted aryl group into screening compounds or advanced intermediates. The defined 3,5-dimethyl substitution pattern can help build structure–activity relationship libraries where positional control is important. Suitability should be confirmed through small-scale experiments because the required reaction conditions differ across molecular targets.
Aryl boronic acids can serve as intermediates in the preparation of complex aromatic molecules used in crop-protection research and specialty chemistry. For these applications, buyers often need consistent batch quality and reliable traceability rather than only a low initial price. When the compound is used in a longer synthesis route, impurity control and reproducible assay can have a direct effect on downstream purification effort.
Process teams may purchase smaller quantities during route screening and later require larger or repeat shipments after a route is selected. I suggest discussing both development and future supply expectations early, even when the first order is modest. This allows the supplier to clarify available pack sizes, production planning, lead-time assumptions, and documentation requirements before the material becomes a critical-path item.
The following data points provide a useful starting point for technical review. They describe the chemical identity, not a guaranteed commercial specification for every batch, so I recommend confirming the supplier’s current documentation before approval.
| Item | Reference Information | Why It Matters |
|---|---|---|
| CAS number | 172975-69-8 | Confirms the intended chemical identity for purchasing and documentation. |
| Molecular formula | C8H11BO2 | Supports formula verification and analytical record review. |
| Molecular weight | Approximately 149.98 g/mol | Used for stoichiometric calculations and solution preparation. |
| Physical form | Typically supplied as a solid | Influences weighing, packaging, handling, and storage planning. |
| Assay and impurities | Supplier-specific | Helps determine whether the material fits research or process requirements. |
I normally request a certificate of analysis showing the tested assay, analytical method, batch number, manufacturing or retest information where applicable, and relevant impurity results. Depending on the project, buyers may also request HPLC, NMR, GC, water-content, or elemental data. These documents should be reviewed against the actual end use rather than requested as generic paperwork.
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First, I identify whether the material is intended for exploratory synthesis, medicinal chemistry, process development, or commercial production. This determines the acceptable documentation depth, quantity, packaging, and quality expectations. A research laboratory may prioritize small packs and rapid availability, while a manufacturing project may prioritize batch consistency, change notification, and supply continuity.
Next, I compare the product name, CAS number, formula, molecular weight, physical form, and proposed assay with the project specification. I also ask how the supplier tests identity and purity, since different analytical methods may detect different classes of impurities. If a specific impurity limit is important, I request written confirmation rather than relying on a general purity statement.
Price should be evaluated together with pack size, minimum order quantity, lead time, shipping conditions, and documentation charges. I ask suppliers to quote the quantity actually required, because unit economics can change substantially between a gram-scale pack and a larger production-oriented pack. I also confirm whether the quoted lead time is based on stock, scheduled production, or an estimated manufacturing window.
A qualified supplier should respond clearly to technical and commercial questions. I look for consistent product naming, transparent specification language, batch traceability, and a practical process for handling document requests. For international procurement, I also verify the shipping address, export paperwork, packaging format, and any restrictions that may affect delivery.
There is no responsible single price for 3,5-Dimethylphenylboronic acid without knowing quantity, assay, packaging, destination, and delivery terms. Small quantities may carry higher unit costs because of packaging, testing, and handling, while larger quantities may require production scheduling. Minimum order quantities are likewise supplier-specific and should be confirmed in the quotation.
Lead time can depend on inventory status, batch release, raw material availability, quality control, and export preparation. I recommend requesting both the earliest available shipment date and the expected lead time for repeat orders. For route development, keeping a qualified second source or an approved alternative can help reduce disruption if timing becomes critical.
At Maison Chemical, I approach 3,5-Dimethylphenylboronic acid as a product that must be matched to the buyer’s technical and commercial requirements. We can discuss the intended application, requested quantity, target specification, packaging preference, and destination before preparing a quotation. This helps separate a simple sample request from a longer-term supply requirement.
For procurement evaluation, I recommend asking us for the available product specification, certificate of analysis format, pack-size options, MOQ, lead time, and shipping terms. Where a project requires additional review, buyers can explain the required analytical documents or quality conditions in advance. Availability, pricing, and delivery timing should always be confirmed for the specific order.
3,5-Dimethylphenylboronic acid CAS 172975-69-8 is a defined aryl boronic acid building block used principally for carbon–carbon bond formation, especially in suitable Suzuki–Miyaura coupling routes. Its reference molecular weight is approximately 149.98 g/mol, but commercial acceptance should be based on the supplier’s current batch documentation and the buyer’s application requirements. The best sourcing decision balances chemical identity, assay, impurity control, packaging, MOQ, lead time, and supplier responsiveness.
If I were qualifying this material for a new project, I would first confirm the CAS number and intended synthetic role, then request the current specification and certificate of analysis. I would compare at least the required quantity, assay expectation, pack size, MOQ, lead time, and shipping terms rather than selecting on price alone. I would also ask whether the supplier can support repeat orders if the route advances.
Maison Chemical can discuss 3,5-Dimethylphenylboronic acid requirements for research, development, and B2B supply programs. To begin, send the required quantity, target specification, destination, packaging preference, and desired delivery window. We can then provide the relevant product and commercial information for your internal technical and purchasing review.
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